Fungicidal (+)-2-(2,4-difluorophenyl)-3-methyl-1-(1H-1,2,4-triaz

Details Fungicidal (+)-2-(2,4-difluorophenyl)-3-methyl-1-(1H-1,2,4-triaz Fungicidal (+)-2-(2,4-difluorophenyl)-3-methyl-1-(1H-1,2,4-triaz

1993-01-25

1994-05-17

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514252, 544238, 536 46, A61K 3150

Patent

active

053128150

ABSTRACT:
(+)-2-(2,4-Difluorophenyl)-3-methyl-1-(1H-1,2,4-triazol-1-yl)-3-(6-(1H-1,2, 4-triazol-1-yl)pyridazin-3-ylthio)butan-2-ol and a pharmaceutically acceptable salt thereof useful as an antifungal agent are disclosed. An inclusion complex of the compound with cyclodextrin can be given either orally or intravenously and has increased absorption when administered orally.

REFERENCES:
patent: 4011218 (1977-03-01), Baldwin et al.
patent: 4256887 (1981-03-01), Novello et al.
patent: 4764604 (1988-08-01), Muller
patent: 4883785 (1989-11-01), Chow et al.
patent: 5177094 (1993-01-01), Itoh et al.

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