Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1990-12-24
1991-09-17
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435254, 435913, C12R 166
Patent
active
050494988
ABSTRACT:
A. parasiticus is employed to hydroxylate 2'-hydroxyterphenyl compounds to terphenyltriols, which can be used to form branched polycarbonates. The hydroxylation reaction is enhanced by maintaining a sufficient amount of a carbon source in the culture medium-reaction medium to maintain the ammonium level below 300 ppm. during the bioconversion phase. Employment of a mutant strain of A. parasiticus which was isolated following ultraviolet light mutagenesis to reduce its tendency to produce aflatoxins is preferred.
REFERENCES:
patent: 4153509 (1979-05-01), Schwartz
patent: 4431736 (1984-02-01), Romesser
patent: 4981793 (1991-01-01), Johnson et al.
Cox et al., "Biotechnol. Biens. 1985", 27, 1395-1402.
Schwartz et al., "Appl. Environ Microbiol.", Apr. 1980, p. 7028, vol. 39, No. 4.
Dietrich David K.
Mobley David P.
Salvo Joseph J.
Spivack James L.
Davis Jr. James C.
General Electric Company
Lilling Herbert J.
Pittman William H.
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