Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-06-13
2006-06-13
Witz, Jean C. (Department: 1651)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C435S077000, C435S254100
Reexamination Certificate
active
07060714
ABSTRACT:
The invention is aimed at discovering a new type of anti-cancer compound which can exert an excellent inhibitory activity against the heparanase. A fungal strainAcremoniumsp. MT70646 (KCTC 8973P) was isolated from the soil. From the culture of the isolated fungal strain, novel compounds that can inhibit both heparinase and heparanase was purified. Therefore, the present invention regards to provide a newly isolated fungal strainAcremoniumsp. MT70646 (KCTC 8973P), its new products, and pharmaceutical agents such as a heparinase inhibitor, a heparanase inhibitor, a metastasis inhibitor and an angeiogenesis inhibitor all of which contain the above new compounds produced by the fungal strain as an active ingredient.
REFERENCES:
patent: 6247900 (2001-10-01), None
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Ahn Jong Seog
Kang Dae Ook
Kim Bo Yeon
Ko Hack Ryong
Mheen Tae Ick
Hanley Susan
Jones Day
Korea Research Institute of Bioscience and Biotechnology
Witz Jean C.
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