Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi
Patent
1987-03-26
1991-04-09
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Fungi
435 34, 435 91, 435171, 4351721, 4351723, 4353201, 435911, 435933, 435935, 536 27, 935 6, 935 9, 935 10, 935 11, 935 14, 935 22, 935 23, 935 24, 935 27, 935 55, 935 59, 935 68, C12N 115, C12N 1511, C12N 1580, C12Q 104
Patent
active
050064711
ABSTRACT:
A drug resistant strain of P.chrysogenum has said drug resistance conferred by heterologous DNA, in particular a heterologous gene(s) under the control of a Penicillium control sequence(s). Drug resistance is especially to sulfonamides, or to trimethoprim or methotrexate by a gene derived from plasmid R388. A vector capable of conferring resistance to methotrexate or sulfonamide on P.chrysogenum, comprises at least one said resistance gene under the control of trpC controlling sequences.
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Carramolino-Fitera Laura
Ortega Agustin P. A.
Sanchez Florentina S.
Susan Victor R.
Antibioticos S.A. of Bravo Murillo 38
Peet Richard C.
Schwartz Richard A.
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