Fungal promoters active in the presence of glucose

Details Fungal promoters active in the presence of glucose Fungal promoters active in the presence of glucose

1995-06-06

2000-01-04

McElwain, Elizabeth F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

4352541, 43525411, 4352543, 4352545, 4352546, 4352561, 4352563, 4352565, 4352567, 4353201, C07H 2104, C12N 1563, C12N 114, C12N 115

Patent

active

06011147&

ABSTRACT:
A method is described for the identification and cloning of promoters that express under a defined environmental condition, such as growth in glucose medium. Using this method, five Trichodermal promoters capable of the high expression of operably linked coding sequences are identified, one of which is the promoter for T. reesei tef1. Also provided are altered cbh1 promoters, altered so that glucose no longer represses expression from such promoter. The invention further provides vectors and hosts that utilize such promoters, and unique fungal enzyme compositions from such hosts.

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