Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi
Patent
1992-07-20
1993-11-09
Robinson, Douglas W.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Fungi
435911, C12N 114, C12N 100
Patent
active
052602150
ABSTRACT:
This invention relates to a fungal microorganism MF5757 (ATCC 74167) isolated from bark discs of Quercus prinus L. (Chestnut Oak) and useful in a fermentation process to form a compound of formula (I): ##STR1## which is a squalene synthetase inhibitor and thus useful as a cholesterol lowering agent.
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Clapp Wendy H.
Kong Yu L.
Polishook Jon D.
Caruso Charles M.
Merck & Co. , Inc.
Robinson Douglas W.
Sevingny Jeffrey J.
Winokur Melvin
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