Fungal alpha-amylase variants

Details Fungal alpha-amylase variants Fungal alpha-amylase variants

2011-02-22

2011-02-22

Raghu, Ganapathirama (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S202000, C435S201000, C435S200000, C435S183000, C435S099000, C435S098000, C435S096000, C426S020000, C536S023200

Reexamination Certificate

active

07892806

ABSTRACT:
The inventors have developed a method of altering the amino acid sequence of a fungal alpha-amylase to obtain variants, and they have used the method to construct such variants. The variants may be useful for anti-staling in baked products. Accordingly, the invention provides a method of constructing fungal alpha-amylase variants based on a comparison of three-dimensional (3D) structures of the fungal alpha-amylase and a maltogenic alpha-amylase. One or both models includes a substrate. The invention also provides novel fungal alpha-amylase variants.

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