Functionalized compositions for improved immobilization

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C540S532000, C558S366000, C536S023100, C536S025300, C435S006120

Reexamination Certificate

active

10293260

ABSTRACT:
The present invention relates to improved covalent coupling of two or more entities such as biomolecules, polymer compositions, organic/inorganic molecules/materials, and the like, including their combinations, through one or more novel reactive groups attached to linker groups of 2–1000 atoms length. The present invention also contemplates the use of bifunctional bridge molecules to link two or more entities, wherein the functional groups of the bridge molecules are the novel reactive groups of the present invention.

REFERENCES:
patent: 5414135 (1995-05-01), Snow et al.
patent: 5736330 (1998-04-01), Fulton
patent: 5981180 (1999-11-01), Chandler et al.
patent: 6046807 (2000-04-01), Chandler
patent: 6057107 (2000-05-01), Fulton
patent: 6139800 (2000-10-01), Chandler
patent: 6146833 (2000-11-01), Miltoh
patent: 6268222 (2001-07-01), Chandler et al.
patent: 6366354 (2002-04-01), Chandler
patent: 6411904 (2002-06-01), Chandler
patent: 6449562 (2002-09-01), Chandler et al.
patent: 6602692 (2003-08-01), Glusenkamp et al.
patent: 960 534 (1957-03-01), None
patent: WO 99/67228 (1999-12-01), None
patent: 00/23478 (2000-04-01), None
patent: 09/035672 (2003-05-01), None
Zhang et al., “Studies on vaccines against cholera. Synthesis of neoglycoconjugates from the hexasaccharide determinant ofVibrio choleraeO:1 serotype Ogawa, by single point attachment or by attachment of the hapten in the form of clusters,” Carbohydrate Research, vol. 321, 1999, pp. 157-167.
Chernyak et al., “Conjugating oligosaccharides to proteins by squaric acid diester chemistry: rapid monitoring of the progress of conjugation, and recovery of the unused ligand,” Carbohydrate Research, vol. 330, 2001, pp. 479-486.
Blixt et al., “Enzymatic glycosylation of reducing oligosaccharides linked to a solid phase or a lipid via a cleavable squarate linker,” Carbohydrate Research, vol. 319, 1999, pp. 80-91.
Tietze et al., “Squaric Acid Diethyl Ester: A New Coupling Reagent for the Formation of Drug Biopolymer Conjugates. Synthesis of Squaric Acid Ester Amides and Diamides,” Chemische Berichte, vol. 124, 1991, pp. 1215-1221.
International Search Report, application No. PCT/US02/36458, mailed May 28, 2004.
Adv. Colloid Interface Sci. 1980, 13-102-140.
Anal. Biochem., 128, 342-350, 1983.
Andreas Frey et al., Bioconjugate Chem. 1999, 10, 562-71.
Bioorg. Khim. 1995, 21(9), 684-90.
E. Siegel in The Chemistry of Synthetic Dyes vol. VI, (Ed. K Venkataraman); 2-108, Academic Press, 1952, Index only.
Fulton et al., Clin. Chem. 1997, 43, 1749-56.
Hermanson, G. T. in Bioconjugate Techniques, Academic Press; N. Y. 1996, Index only.
Ivan L. Valuev et al., Biomaterials, 1998, 19, 41-43.
J. Macromol. Sci. .Chem. 1979, A-13, 603-632.
Kettman et al., Cytometry, 1998, 33, 234-43.
Margel et al., J. Polym. Sci., 1991, A-29 347-355.
Maxime A. Gilles et. al., Anal. Biochem., 1990, 184, 244-48.
McDade et al., Med. Dev. Diag. Indust. 1997, 19(4), 75-82.
McHugh, Methods Cell Biol. 1994, 42, 575-95.
Nikiforov et al., Nucleic Acid Res. 1994, 22, 4167-75.
R. Arshady, (Biomaterials, 1993, 14, 5-15)S.
Rembaum et al. (Br. Poly J. 1978, 10, 275-280.
Ugelstad et al., (Makromol., Chem. 1979, 180, 737-44.
Upson, (J. Poly., Sci., Polym. Symp.(1985), 72, 45.
Vivien W. F. Chan et. al., Biochem. Biophys. Res. Communications., 1988, 151(2), 709-16.
The Chemistry of Synthetic Dyes, Chapter 1 entitle Reactive Dyes: Reactive Groups by E. Siegel, © 1972 by Academic Press, pp. 1-209.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Functionalized compositions for improved immobilization does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Functionalized compositions for improved immobilization, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Functionalized compositions for improved immobilization will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3816259

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.