Functionalised maltosyl fluoride as glycosyl donor in the...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S096000, C435S097000, C435S101000

Reexamination Certificate

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07087746

ABSTRACT:
Disaccharides of formula (I) are derived from a-maltosyl fluoride, wherein R1and R2are defined. Such disaccharides are useful as glycosyl donors in transglycosylation reactions catalyzed by glycoside-hydrolazes or in transfer reactions catalyzed by transglycosylases during the preparation of oligosaccharides or polysaccharides.

REFERENCES:
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patent: 1098498 (1989-04-01), None
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Cottaz et al. Chemoenzymatic Approach to the Preparation of Regioselctively Modified Cyclodextrins. The Substrate Specificity of the Enzyme Cyclodextrin Glucosyltransferase (CGTase). 1991., J. Chem Soc. Perkin Trans 1. pp. 2235-2241.
Faijes et al. Oligosaccharide Synthesis by Coupled endo-Glycosynthases of Different Specificit: A Straightforward Preparation of Two Mixed-Linkage Hexasaccharide Substrates of 1,3/1,4-B-Glucanases. 2001. Chem. Eur J. 7, No. 21. pp. 4651-4655.
Fort et al. Highly Efficient Synthesis of B(1-4)-Oligo- and -Polysacharides Using Mutant Cellulase. 2000. J. Am. Chem. Soc. 122. pp. 5429-5437.
C. Apparu et al.:, “A highly effieicent chemoenzymatic synthesis of 6A, 6D-diiode alfa-cyclodextrin” Carbohydrate Letters, vol. 1, 1995, pp. 349-352, XP008003716, le document en entier.
S. Fort et al.:, “Stepwise synthesis of cellodextrins assisted by a mutant cellulase”, Israel Journal of Chemistry, vol. 40, 2000, pp. 217-221, XP008003718 le document en entier.
S.-I. Shoda et al.., “Enzymatic polymerization of activated glycosyl monomers for highly selective polysaccharide synthesis”, Korea Polmer Journal, vol. 4, No. 2, 1996, pp. 112-116, XP008003717 le document en entier.
Bornaghi L et al:, “Transfer reactions catalyzed by cyclodextrin glucosyltransferase using 4-thiomaltosyl and C-maltosyl fluorides as artificial donors”, Carbohydrate Research, Elsevier Scientific Publishing Company. Amsterdam, NL, vol. 305, No. 3-4, Dec. 1997, pp. 56 1-568, XP004191939, ISSN: 0008-6215, le document en entier.

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