Functional reconstitution of SCID-bo mice with bovine fetal hema

Details Functional reconstitution of SCID-bo mice with bovine fetal hema Functional reconstitution of SCID-bo mice with bovine fetal hema

1995-06-07

1999-07-20

Stanton, Brian R.

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

424 931, 424520, 424582, 424570, A61K 4800

Patent

active

059258020

ABSTRACT:
The present invention provides a non-human chimeric mammal, comprising a severe-combined immunodeficient mammal engrafted with bovine immune system tissues, wherein said chimeric mammal is functionally reconstituted. Also provided is a method of producing a functionally reconstituted scid-bo mouse with bovine fetal hematopoietic tissues.

REFERENCES:
Boermans et al. "Engraftment of severe combined immune deficient/beige mice with bovine foetal lymphoid tissues," Vet. Imm. and Immunopathology, vol. 34: 273-289, 1992.
Hoffmann-Fezer et al., "Peritoneal sanctuary for human lymphopoiesis in SCID mice injected with human peripheral blood lymphocytes from EBV negative donors," European J. of Immunology, vol. 22 (12): 3161-3166, Dec. 1992.
Sanhadji et al., "Fetal liver cell transplantation in various murine models," Bone Marrow Transplantation, vol. 9 (Suppl. 1): 77-82, Jan. 1992.

Affiliated with

Also associated with

Rating

Functional reconstitution of SCID-bo mice with bovine fetal hema does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Functional reconstitution of SCID-bo mice with bovine fetal hema, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Functional reconstitution of SCID-bo mice with bovine fetal hema will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1323234