Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Chemical stimulation of growth or activity by addition of...
Patent
1995-05-26
1998-06-16
Hutzell, Paula K.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Chemical stimulation of growth or activity by addition of...
435 71, 435 72, 435 721, 435 792, 436 63, 436503, C12N 138, G01N 33566, G01N 33567
Patent
active
057669228
ABSTRACT:
The extracellular domain of RPTP.beta. is the ligand for contactin and its binding results in neurite growth and differentiation. The invention encompasses compounds that mimic, enhance, or suppress the effects of the ligand for contactin, assays for the identification of such compounds, and the use of such compounds to treat neurologic diseases including those characterized by insufficient, aberrant, or excessive neurite growth, differentiation or survival.
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Krishna Rao, A. S. M., and R
Hutzell Paula K.
Krikorian Jacqueline G.
Sugen Inc.
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