Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus esters
Reexamination Certificate
2006-09-05
2006-09-05
Crane, L. E. (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Phosphorus esters
C536S025300
Reexamination Certificate
active
07102024
ABSTRACT:
Hydrazino, oxyamino and carbonyl-based reagents and methods for incorporation into oligonucleotides during their solid phase synthesis are provided. Modified oligonucleotides are provided that incorporate the reagents provided here in. Immobilized oligonucleotides and oligonucleotide conjugates that contain covalent hydrazone or oxime linkages are provided. Methods for preparation of surface bound oligonucleotides are provided. Methods for the preparation of oligonucleotide conjugates are also provided.
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Hogrefe Richard I.
Schwartz David A.
Crane L. E.
David Waller & Assoc.
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