Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-04-08
1997-08-12
Houtteman, Scott W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
546108, 436543, 436172, 25230121, 552638, C12Q 168
Patent
active
056564260
ABSTRACT:
Novel acridinium esters that are useful, either alone or when incorporated into liposomes, as chemiluminescent agents in binding assays (e.g., immunoassays and gene probe assays) with improved-sensitivity are disclosed. In addition, the synthesis of these esters and their use in assays for detecting an analyte is described. In particular, assays for testosterone and the Rubella virus are disclosed.
REFERENCES:
patent: 4031117 (1977-06-01), Rao
patent: 4197286 (1980-04-01), Rao
patent: 4745181 (1988-05-01), Law et al.
patent: 5241070 (1993-08-01), Law
patent: 5281712 (1994-01-01), McCapra et al.
patent: 5283334 (1994-02-01), McCapra
patent: 5284951 (1994-02-01), McCapra et al.
patent: 5284952 (1994-02-01), Ramakrishnan
patent: 5290936 (1994-03-01), Beheshti et al.
patent: 5321136 (1994-06-01), McCapra
Hammond et al., J. Bioliminescence and Chemiluminescence 6:35-43 (1991).
Weeks et al., Clin. Chem. 29(8):1474-1479 (1983).
Matthews et al., Analytical Biochemistry 169, 1-25 (1988).
Bonfanti, C. et al., 1985a, J. Virolog. Meth. 11: 161-170.
Bonfanti, C. et al., 1985b, J. Clin. Microbio. 21(6): 963-968.
Crosby, S.R. et al., 1986, J. Steroid Biochem. 25: 957-962.
Forsgren, M., 1985, Reviews of Infec. Diseases 7(Supp.1): S129-S132.
Isaac and Payne, 1982, J. Med. Virology 10: 55-64.
Law, S.-J. et al., 1989, J. Biolum. and Chemilum. 4: 88-98.
Rao and Moore, Jr. 1976, Steroids 28: 101-109.
Rao and Taraporewala, 1993, Steroids 57: 154-161.
Ruegg et al, 1974, 6 Int. J. Peptide Protein Res. 447-456.
Seppanen, H., 1990, J. Clin. Microbio. 28(4): 719-723.
Steece, R. S. et al., 1984, J. Clin. Microbio. 19(6): 923-925.
White, A. et al., 1985, J. Steroid Biochem. 23: 981-989.
Wielaard, F. et al., 1985, J. Virolog. Meth. 10: 349-354.
Connolly Peter B.
Jiang Qingping
Kilroy John P.
Law Say-Jong
McCudden Constance R.
Blackburn Robert
Chiron Diagnostics Corporation
Houtteman Scott W.
Morgenstern Arthur S.
LandOfFree
Functionaized hydrophilic acridinium esters does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Functionaized hydrophilic acridinium esters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Functionaized hydrophilic acridinium esters will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-159210