Function regulator for retinoid relative receptor

Details Function regulator for retinoid relative receptor Function regulator for retinoid relative receptor

2007-05-29

2007-05-29

Stockton, Laura L. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

Reexamination Certificate

active

10481033

ABSTRACT:
The present invention provides a retinoid-related receptor (except retinoic acid receptors) function regulating agent comprising a compound represented by the formula:wherein one of R1and R2is an optionally substituted monocyclic aromatic hydrocarbon group or an optionally substituted monocyclic aromatic heterocyclic group containing one heteroatom, and the other is a hydrogen atom and the like; B is a 5- or 6-membered heterocycle (except 1,3-azole); A is an optionally substituted aromatic hydrocarbon group or an optionally substituted aromatic heterocyclic group; and R3is a hydrogen atom and the like, or a salt thereof, which is useful as an agent for the prophylaxis or treatment of diabetes mellitus, hyperlipidemia, impaired glucose tolerance or the like.

REFERENCES:
patent: 5977108 (1999-11-01), Kikuchi et al.
patent: 6020339 (2000-02-01), Perrier et al.
patent: WO 97/02244 (1997-01-01), None
patent: WO 97/34869 (1997-09-01), None
patent: WO 00/01679 (2000-01-01), None
Bruno et al., Expert Opinion Emerging Drugs, (2005), 10(4), pp. 747-771.
Park, Diabetes Research and Clinical Practice 66S (2004), S33-S35.
Brooks, et al. “Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol-4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists” Journal of Medicinal Chemistry 44(13): 2061-2064(2001).
Willson, et al. “The PPARs: From Orphan Receptors to Drug Discovery” Journal of Medicinal Chemistry 43(4): 527-550(2000).

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