Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-05-02
2010-11-23
Aeder, Sean E (Department: 1642)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C530S387100
Reexamination Certificate
active
07838645
ABSTRACT:
The present invention relates to a new molecular pathway in which activation of the receptor-interacting protein (RIP, a serine-threonine kinase) and Jun N-terminal kinase induce cell death with the morphology of autophagy. Further, autophagic death is induced by caspase 8 inhibition and expression of the mammalian genes ATG7 and beclin.
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Alva Ajjai
Baehrecke Eric H.
Lenardo Michael J.
Li Yu
Aeder Sean E
Hultquist Steven J.
Intellectual Property / Technology Law
National Institutes of Health
Reynolds Kelly K.
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