Fully human antibodies directed against the human...

Details Fully human antibodies directed against the human... Fully human antibodies directed against the human...

2011-06-28

2011-06-28

Blanchard, David J. (Department: 1643)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

C424S141100, C424S142100, C424S155100, C424S181100, C424S183100, C435S069600, C435S070210, C435S330000, C435S449000, C530S388100, C530S388150, C530S388220, C530S388800, C530S391700

Reexamination Certificate

active

07968093

ABSTRACT:
This invention relates to human antibodies that bind to human insulin-like growth factor-1 receptor (IGF-IR), to derivatives of these antibodies (Fabs, single chain antibodies, bi-specific antibodies, or fusion proteins), and to uses of the antibodies and derivatives in therapeutic, and diagnostic methods. The invention relates to nucleic acids encoding the anti-IGF-IR, methods of generating the antibodies and expression. The invention further relates to combination therapies using ant-IGF-IR antibodies with anti-neoplastic drugs.

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