Fully human antibodies against human 4-1BB

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387100, C530S387900, C530S388100, C530S388200, C530S388220, C530S388750, C424S142100, C424S130100, C424S139100, C424S141100, C424S143100, C424S152100, C424S154100

Reexamination Certificate

active

10961567

ABSTRACT:
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.

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