Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Reexamination Certificate
2011-03-01
2011-03-01
Gambel, Phillip (Department: 1644)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
C424S130100, C424S133100, C424S141100, C424S142100, C424S143100, C424S152100, C424S172100, C530S387100, C530S387300, C530S388100, C530S388150, C530S388200, C530S388220
Reexamination Certificate
active
07897149
ABSTRACT:
Novel fully human anti-VAP-1 antibodies and fragments thereof are disclosed. Nucleic acids encoding anti-VAP-1 antibodies or fragments thereof, as well as expression vectors and host cells incorporating these nucleic acids for the recombinant expression of anti-VAP-1 antibodies are also given. Pharmaceutical compositions comprising said antibodies and therapeutic uses thereof are also disclosed.
REFERENCES:
patent: 5580780 (1996-12-01), Jalkanen et al.
patent: WO 93/25582 (1993-12-01), None
patent: WO 98/53049 (1998-11-01), None
patent: WO 03/084469 (2003-10-01), None
patent: WO 03/093319 (2003-11-01), None
Rudikoff et al., Proc Natl Acad Sci USA 79: 1979-1983, 1982.
Colman, Research in Immunology 145: 33-36, 1994.
Kussie et al., J. Immunol. 152: 146-152, 1994.
Chen et al., EMBO J., 14: 2784-2794, 1995.
Bendig, Methods: A Companion to Methods in Enzymology 1995; 8:83-93, 1995.
Padlan et al., PNAS 86: 5938-5942, 1989.
Kirton, C.M., et al., “Function-blocking antibodies to human vascular adhesion protein-1: A potential anti-inflammatory therapy,”Eur. J. Immunol. 35:3119-3130, VCH Verlagsgesellschaft (2005).
Kurkijärvi, R., et al., “Circulating Form of Human Vascular Adhesion Protein-1 (VAP-1): Increased Serum Levels in Inflammatory Liver Diseases,”J. Immunol. 161:1549-1557, American Association of Immunologists (1998).
van Dijk, M.A. and van de Winkel, J.G.J., “Human antibodies as next generation therapeutics,”Curr. Opin. Chem. Biol. 5:368-374, Current Biology (2001).
International Search Report for International Application No. PCT/FI2008/050199, mailed on Jul. 29, 2008, National Board of Patents and Registration of Finland, Helsinki, FI.
Mikkola Jari
Smith David John
Vainio Jani
Vainio Petri
Vuorio Päivi
Biotie Therapies Corp.
Birch & Stewart Kolasch & Birch, LLP
Gambel Phillip
LandOfFree
Fully human anti-VAP-1 monoclonal antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fully human anti-VAP-1 monoclonal antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fully human anti-VAP-1 monoclonal antibodies will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2780078