Fullerene coated surfaces and uses thereof

Details Fullerene coated surfaces and uses thereof Fullerene coated surfaces and uses thereof

1992-06-22

1994-05-10

Warden, Robert J.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an organic...

435174, 4352402, 43524023, 435240243, 435284, C12M 300, C12N 500, C12N 1100, C12N 1102

Patent

active

053106695

ABSTRACT:
Substrates having a surface coated with fullerene and a substance attached thereto are disclosed. Cell culture substrates having a fullerene-coated surface are useful in methods of growing cells on the fullerene-coated surface. Methods of preparing cell culture substrates for cell attachment and growth by coating a surface with fullerene are provided. Cells can be grown on a fullerene-coated surface in the presence of a substance such as a cytokine, growth hormone or a drug, to evaluate the interaction between the substance and the cells. Methods for increasing cell membrane premability and for introducing a substance, such as a DNA or RNA vector, into a cell are also provided.

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