Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-03-22
2005-03-22
Winkler, Ulrike (Department: 1648)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C424S189100, C424S218100, C435S069100, C435S320100, C536S023100
Reexamination Certificate
active
06870043
ABSTRACT:
GB virus C (GBV-C or hepatitis G virus) is a recently described flavivirus that frequently leads to chronic viremia in humans. Although associated with acute post-transfusion hepatitis, it is not clear if GBV-C is pathogenic for humans. A full-length cDNA was constructed from the plasma of a person with chronic GBV-C viremia. Peripheral blood mononuclear cells (PBMCs) transfected with full-length RNA transcripts from this GBV-C clone resulted in viral replication, demonstrating an isolated infectious GBV-C nucleic acid molecule. In addition to composition involving an isolated infectious GBV-C nucleic acid molecule, the present invention concerns methods of inhibiting and treating HIV infections.
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Schmidt Warren
Stapleton Jack
Wünschmann Sabina
Xiang Jinhua
Fulbright & Jaworski L.L.P.
The University of Iowa Research Foundation
Winkler Ulrike
LandOfFree
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