Fucosyltransferase genes and uses thereof

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

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530350, 435 691, 4352523, 4353201, 536 232, 536 235, 536 2353, C12N 910, C07K 100, C12P 2106, C07H 2104

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active

058587527

ABSTRACT:
Purified DNA encoding .alpha.(1,3)fucosyltransferase and the recombinant proteins expressed from such DNA are disclosed. The recombinant fucosyltransferase polypeptides are used to fucosylate proteins to produce therapeutics useful for the treatment of disease, e.g., an adverse immune reaction such as septiciemia or septic shock.

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