FSH mutants

Details FSH mutants FSH mutants

2006-12-21

2010-06-22

Nickol, Gary B (Department: 1647)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Hormone or other secreted growth regulatory factor,...

C514S002600, C530S397000, C530S398000, C530S300000

Reexamination Certificate

active

07740862

ABSTRACT:
FSH mutants with increased glycosylation and longer half-lives are described. The use of FSH mutants for inducing folliculogenesis in human patients is also described.

REFERENCES:
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patent: WO 2004/050679 (2004-06-01), None
patent: WO 2005/020934 (2005-03-01), None
patent: WO 2007/084441 (2007-07-01), None
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Yoo, J. et al. “COOH-terminal Amino Acids of the α Subunit Play Common and Different Roles in Human Choriogonadotropin and Follitropin”The Journal of Biological Chemistry, Jun. 25, 1993, pp. 13034-13042, vol. 268, No. 18.

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