Fructosyl amino acid oxidase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

Reexamination Certificate

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C435S191000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

07091017

ABSTRACT:
The present invention provides a novel fructosyl amino acid oxidase that is excellent in thermal stability. Moreover, the present invention provides a fructosyl amino acid oxidase gene encoding the novel fructosyl amino acid oxidase, a recombinant DNA in which the gene is inserted into a vector DNA, a transformant or transductant containing this gene, and a process for producing the novel fructosyl amino acid oxidase, which comprises culturing the transformant or transductant in a medium and collecting the novel fructosyl amino acid oxidase from the culture product.

REFERENCES:
patent: 61-268178 (1986-11-01), None
patent: 11-155579 (1999-06-01), None
Sequence search alignment between Applicant's Seq Id No.: 2 and Accession No. Q8RIU8.
T. Horiuchi, et al., Agric. Biol. Chem., vol. 53, No. 1, XP-002022262, pp. 103-110, “Purification and Properties of Fructosyl-Amino Acid Oxidase from Corynebacterium SP. 2-4-1”, 1989.
Z. Lin, et al., Biotechnol. Prog., vol. 15, No. 3, XP-000892792, pp. 467-471, “Functional Expression of Horseradish Peroxidase inE. coliby Directed Evolution”, May 1999.
R. Sakaue, et al., Applied and Environmental Microbiology, vol. 69, No. 1, XP-002286929, pp. 139-145, “Thermostabilization of Bacterial Fructosyl-Amino Acid Oxidase by Directed Evolution”, Jan. 2003.

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