Fructose-bisphosphate aldolase regulatory sequences for gene...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S006120, C435S007310, C435S069100, C435S069900, C435S320100

Reexamination Certificate

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10987548

ABSTRACT:
The regulatory sequences (i.e., promoter regions, introns and enhancers) associated with theYarrowia lipolyticagene encoding fructose bis-phospate aldolase (FBA1) have been found to be particularly effective for the expression of heterologus genes in oleaginous yeast. The promoter regions of the invention have been shown to drive high-level expression of genes involved in the production of ω-3 and ω-6 fatty acids.

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