Frit material and bonding method for microfluidic separation...

Liquid purification or separation – With means to add treating material – Chromatography

Reexamination Certificate

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C210S656000, C073S061520, C422S070000, C422S105000

Reexamination Certificate

active

07153421

ABSTRACT:
A multi-layer microfluidic separation device comprises a polymeric membrane frit that may be securely bonded within the device and minimizes lateral wicking. Stationary phase material having an average particle size is retained by a frit having an average pore size that is smaller than the average particle size. In one embodiment, a secure bond is ensured by treating the polymer to match its surface energy to that of the materials to which it is bound. Treatments include plasma treatment, irradiation and the application of acids.

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