Freeze protective shipping units

Details Freeze protective shipping units Freeze protective shipping units

1991-01-14

1993-01-26

Makay, Albert J.

Refrigeration

Portable, commodity-containing

116219, 624572, 206570, B65D 8118, F25D 308

Patent

active

051813947

ABSTRACT:
Disclosed are shipping and/or storage units for containers of liquid compositions, such as solutions of biologically active proteins, which are susceptible to physicochemical change upon freezing. Preferred container holders have double sidewalls and a freeze indicator adjacent a container-accommodating cavity. A phase change material such as a carboxymethylcellulose gel is disposed in the enclosed space between sidewalls and freezes at a temperature higher than the nucleation temperature of the composition. A freeze indicator provides an irreversible visual signal upon reaching a temperature intermediate the nucleation temperature of the liquid composition and the freezing temperature of the phase change material.

REFERENCES:
patent: 3429141 (1966-02-01), Halseth
patent: 4145918 (1979-03-01), Couch et al.
patent: 4191125 (1980-03-01), Johnson
patent: 4250998 (1981-02-01), Taylor
patent: 4280336 (1981-07-01), Taylor
patent: 4573581 (1986-03-01), Galloway et al.
patent: 4738364 (1988-04-01), Yeager
patent: 4850484 (1989-07-01), Denman
patent: 4989419 (1991-02-01), Brando et al.

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