Freeze-dried polymer dispersions and the use thereof in preparin

Details Freeze-dried polymer dispersions and the use thereof in preparin Freeze-dried polymer dispersions and the use thereof in preparin

1990-03-05

1994-07-05

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424461, 424462, 424464, 424465, 424469, 424470, 424480, 424481, 424482, 424485, 424489, 424486, 424495, 514937, A61K 914

Patent

active

053265726

ABSTRACT:
Freeze-dried polymer latices, which can be reconstituted in water to give aqueous polymer dispersions having high polymer solids content, are described. The reconstituted polymer dispersions are useful in preparing sustained-release drug formulations, particularly of water-soluble drugs, by the wet granulation method without over wetting.

REFERENCES:
patent: 2800463 (1957-07-01), Morrison
patent: 3942261 (1976-03-01), Hirata et al.
patent: 4330338 (1982-05-01), Banker
patent: 4652442 (1987-03-01), Hopfgartner et al.

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