Freeze-dried liposome mixture containing cyclosporin

Details Freeze-dried liposome mixture containing cyclosporin Freeze-dried liposome mixture containing cyclosporin

1988-07-07

1990-10-16

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 264 43, 424420, 4284022, 514885, A61K 9127, A61K 3722, A61K 4505

Patent

active

049633627

ABSTRACT:
The invention provides a freeze-dried potential liposome mixture having an amphipathic lipid and a cyclosporin or derivative thereof for use in possible liposome delivery of cyclosporin into cells. A method to produce the freeze-dried mixture is also disclosed. When reconstituted to yield liposomes in an aqueous medium, substantially all of the cyclosporin present in the freeze-dried mixture is encapsulated in the liposomes.

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