Freeze-dried compositions

Details Freeze-dried compositions Freeze-dried compositions

1998-04-28

1999-09-21

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31415

Patent

active

059554886

ABSTRACT:
The invention relates to a freeze-dried dosage form for oral administration capable of being rapidly disintegrated in the mouth comprising ondansetron in the form of its free base or a pharmaceutically acceptable solvate thereof and one or more pharmaceutically acceptable excipients. Methods for the manufacture of such compositions and for their use in the treatment of conditions mediated through the action of 5-hydroxytryptamine (5HT) at 5HT.sub.3 receptors are also described.

REFERENCES:
patent: 5288497 (1994-02-01), Stanley et al.
Remington's Pharmaceutical Sciences, 16th ed. pp. 1111 and 1225-1227, 1980.

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