Free radical scavengers useful for reducing autoflourescence in

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 266, 435 5, 435 721, C12Q 168, C12Q 170, C07H 2102, G01N 33567

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056655460

ABSTRACT:
Assays for target molecules in cells and viruses whereby the use of free radical scavengers leads to decreased autofluorescence.

REFERENCES:
Poot, et al., Autofluorescence of Human Skin Fibroblasts During Growth Inhibition and in vitro Ageing, Gerontology, v. 31, pp. 158-165 (1985).
Deamer, et al., Autofluorescent Structures in Cultured WI-38 Cells, Archives of Biochemistry and Biophysics, v. 165, pp. 421-426 (1974).
Rattan, et al., Autofluorescence as an Index of Ageing in Human Fibroblasts in Culture, Bioscience Reports, v. 2, pp. 561-567 (1982).
McKenna, et al., Kinetic Analysis of the Free-Radical-Induced Lipid Peroxidation in Human Erythrocyte Membranes Evaluation of Potential Antioxidants Using CIS, Analytical Biochemistry, v. 196, pp. 443-450 (1991).
Kan, et al., Effect of Vitamin E on the Accumulation of Fluorescent Material in Cultured Cerebral Cortical Cells of Mice, Experimental Gerontology, v. 26, pp. 365-374 (1991).
Trask, Trends in Genetics 7(5): 149-154 (1991) "Fluorescence In Situ Hybridization".

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