Free radical based biochemical method for detecting substances i

Details Free radical based biochemical method for detecting substances i Free radical based biochemical method for detecting substances i

1984-12-24

1987-03-24

Marantz, Sidney

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

436536, 436538, 436803, 436817, G01N 3353, G01N 33532, G01N 33537

Patent

active

046525327

ABSTRACT:
A biochemical method of assaying for ligand molecules in fluids based on the specific interaction of a ligand and a ligand-recognition molecule that binds the ligand wherein a free radical forming group is covalently coupled to label either a ligand sought to be assayed or the ligand recognition molecule or is internally generated from the ligand or ligand recognition molecule, and directly or indirectly assaying for the ligand.

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Tan, C. et al., "Membrane Immunoassay: A Spin Membrane Immunoassay for Thyroxine," Methods in Enzymology, Eds. J. Langone and H. Vinakis, Academic Press, New York, 1981, 74:151-161.
Yang, G., and E. Copeland, "Spin Immunoassay," Methods in Enzymology, Eds. J. Langone and H. Vinakis, Academic Press, New York, 1981, 74:140-151.

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