Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1987-08-07
1989-06-27
Davis, Curtis R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514559, 514560, A61K 3123
Patent
active
048430951
ABSTRACT:
Free fatty acids form fish oil, DHA and EPA, are useful in treating rheumatoid arthritis. The free fatty acids were an order of magnitude more effective in treating arthritis than unhydrolyzed fatty acids derived from fish oil.
REFERENCES:
patent: 4302447 (1981-10-01), Horrobin
patent: 4472432 (1984-09-01), Iwamura et al.
patent: 4512996 (1985-04-01), Somers
patent: 4526902 (1985-07-01), Rubin
"Effects of Manipulation of Dietary Fatty Acids on Clinical Manifestations of Rheumatoid Arthritis", The Lancet, Jan. 26, 1985, pp. 184-187.
"Dietary Fish Oil Augments of the Induction of Arthritis in Rats Immunized With Type II Collagen.sup.1 ", The Journal of Immunology, vol. 132, No. 2, Feb., 1984, pp. 725-729.
"Dietary Fish Oil Modulates Macrophage Fatty Acids and Decreases Arthritis Susceptibility in Mice", Journal of Experimental Medicine, vol. 162, Oct. 1985, pp. 1336-1349.
"Fish-Oil Fatty Acid Supplentation in Active Rheumatoid Arthritis", Annals of Internal Medicine, Apr., 1987, vol. 106, No. 4, pp. 497-503.
Century Laboratories, Inc.
Davis Curtis R.
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