Fredericamycin derivatives as medicaments for treating tumours

Details Fredericamycin derivatives as medicaments for treating tumours Fredericamycin derivatives as medicaments for treating tumours

2007-07-17

2007-07-17

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S015000, C546S018000

Reexamination Certificate

active

10520421

ABSTRACT:
The invention relates to novel fredericamycin derivatives of general formula (Ia) or (Ib), to medicaments containing the fredericamycin derivatives or salts thereof, and to the use of the fredericamycin derivatives for treating diseases, especially tumor diseases.

REFERENCES:
patent: 4584377 (1986-04-01), Yokoi et al.
patent: 4673678 (1987-06-01), Misra
patent: 5166208 (1992-11-01), Kelly et al.
Latham, Michael et al.: “Inhibition of Topoisomerases By Fredericamycin A,” Cancer Chemotherapy and Pharmacology (1989) 24: 167-171.
Warnick-Pickle, Dana J. et al.: “Fredericamycin A. A New Antitumor Antibiotic Biological Properties,” Journal of Antibiotics (1981) vol. 34, No. 11, pp. 1402-1407.

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