Fredericamycin A derivatives

Details Fredericamycin A derivatives Fredericamycin A derivatives

1991-10-09

1992-11-24

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 15, C07D22120, A61K 31435

Patent

active

051662086

ABSTRACT:
The invention pertains to derivatives of fredericamycin A, their preparation and pharmaceutical uses as antitumor agents.

REFERENCES:
patent: 4584377 (1986-04-01), Yokoi et al.
patent: 4673678 (1987-06-01), Misra
Bolger et al., J. Org. Chem., 56, 2115 (1991).
Merck Index, p. 667 (11th. ed., 1989).
Kelly et al., J. Am. Chem. Soc., 110, 6471 (1988).
R. C. Panday et al., J. Antibiot., 34, 1389 (1981).
R. Misra et al., J. Am. Chem. Soc., 104, 4478 (1982).
R. Misra et al., J. Antibiot., 40, 786 (1987).
K. M. Byrne et al., Biochemistry, 24, 478 (1985).
D. J. Warnick-Pickle et al., J. Antibiot, 34, 1402 (1981).
R. Misra, J. Antibiot., 51, 976 (1988).
N. S. Dalal et al., Biochemistry, 28, 748 (1989).
M. D. Latham et al., Cancer Chemother. Pharmacol., 24, 167 (1989).
T. R. Kelly et al., J. Am. Chem. Soc., 108, 7100 (1986).
A. V. R. Rao et al., J. Chem. Soc., Chem. Commun., 1119 (1984).
K. A. Parker et al., Tetrahedron Lett., 26, 2181 (1985).
A. S. Kende et al., Tetrahedron Lett., 26, 3063 (1985).
G. Eck et al., Tetrahedron Lett., 26, 4723 (1985).
G. Eck et al., Tetrahedron Lett., 26, 4725 (1985).
M. Braun et al., Tetrahedron Lett., 27, 179 (1986).
K. R. Acharya et al., Acta Crystallogr., Sect. C. Cyst. Struct. Commun., 42, 334 (1986).
R. D. Bach et al., J. Org. Chem., 51, 749 (1986).
S. M. Bennett et al., J. Chem. Soc., Chem. Commun., 878 (1986).
R. D. Bach et al., Tetrahedron Lett., 27, 1983 (1986).
K. A. Parker et al., Tetrahedron Lett., 27, 3835 (1986).
A. V. R. Rao, In "Organic Synthesis Modern Trends, Proceedings of the 6th IUPAC Symposium", Chizhov, O. S. Ed.; Blackwell, Oxford, p. 75 (1987).
M. A. Ciufolini et al., Tetrahedron Lett., 28, 171 (1987).
K. A. Parker et al., J. Org. Chem., 52, 183 (1987).
U. R. Khire et al., Indian J. Chem., Sect. B, 26, 195 (1987).
A. V. R. Rao et al., Tetrahedron Lett., 28, 451 (1987).
A. V. R. Rao et al., Tetrahedron Lett., 28, 455 (1987).
G. Mehta et al., Tetrahedron Lett., 28, 479 (1987).
D. L. J. Clive et al., J. Heterocycl. Chem., 24, 509 (1987).
Y. Tanoue et al., Bull. Chem. Soc. Jpn., 60, 2927 (1987).
S. N. Naik et al., Synth. Commun., 18, 633 (1988).
A. V. R. Rao et al., Indian J. Chem., Sect. B., 27, 1065 (1988).
M. A. Ciufolini et al., J. Org. Chem., 53, 4149 (1988).
J. C. Evans et al., J. Org. Chem., 53, 5519 (1988).
M. Julia et al., Heterocycles, 28, 71 (1989).
A. V. R. Rao et al., J. Chem. Soc., Chem. Commun, 400 (1989).
M. Toyota et al., Tetrahedron Lett., 30, 829 (1989).
D. L. Boger et al., Tetrahedron Lett., 30, 2037 (1989).
I. S. Aidhen et al., Tetrahedron Lett., 30, 5323 (1989).
B. Pandey et al., J. Chem. Soc., Chem. Commun., 1791 (1990).
D. L. Boger et al., J. Org. Chem., 55, 1919 (1990).
A. V. R. Rao et al., Indian J. Chem., Sect. B, 30B, 723 (1991).
L. Set et al., J. Chem. Soc., Chem. Commun., 1205 (1985).
D. L. J. Clive et al., J. Chem. Soc., Chem. Commun., 1755 (1991).
D. J. Clive et al., J. Chem. Soc., Perkin Trans I, 1433 (1991).
D. L. J. Clive et al., J. Chem. Soc., Chem. Commun., 1520 (1987).
D. L. J. Clive et al., Tetrahedron Lett., 32, 7159 (1981).

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