Fragmented polymeric compositions and methods for their use

Details Fragmented polymeric compositions and methods for their use Fragmented polymeric compositions and methods for their use

1998-02-27

2000-05-23

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

424422, 424423, 424426, 524916, A61K 900, A61F 1300, A61F 200

Patent

active

060663251

ABSTRACT:
Cross-linked hydrogels comprise a variety of biologic and non-biologic polymers, such as proteins, polysaccharides, and synthetic polymers. Such hydrogels preferably have no free aqueous phase and may be applied to target sites in a patient's body by extruding the hydrogel through an orifice at the target site. Alternatively, the hydrogels may be mechanically disrupted and used in implantable articles, such as breast implants. When used in vivo, the compositions are useful for controlled release drug delivery, for inhibiting post-surgical spinal and other tissue adhesions, for filling tissue divots, tissue tracts, body cavities, surgical defects, and the like.

REFERENCES:
patent: 4013078 (1977-03-01), Feild
patent: 4291013 (1981-09-01), Wahlig et al.
patent: 4347234 (1982-08-01), Wahlig et al.
patent: 4749689 (1988-06-01), Miyata et al.
patent: 4803075 (1989-02-01), Wallace et al.
patent: 4832686 (1989-05-01), Anderson
patent: 4925677 (1990-05-01), Feijen
patent: 4946870 (1990-08-01), Partain, III et al.
patent: 5007916 (1991-04-01), Linsky et al.
patent: 5017229 (1991-05-01), Burns et al.
patent: 5041292 (1991-08-01), Feijen
patent: 5061274 (1991-10-01), Kensey
patent: 5061492 (1991-10-01), Okada et al.
patent: 5080893 (1992-01-01), Goldberg et al.
patent: 5108421 (1992-04-01), Fowler
patent: 5126141 (1992-06-01), Henry
patent: 5129882 (1992-07-01), Weldon et al.
patent: 5134229 (1992-07-01), Saferstein et al.
patent: 5135751 (1992-08-01), Henry et al.
patent: 5140016 (1992-08-01), Goldberg et al.
patent: 5192300 (1993-03-01), Fowler
patent: 5196185 (1993-03-01), Silver et al.
patent: 5204382 (1993-04-01), Wallace et al.
patent: 5275616 (1994-01-01), Fowler
patent: 5300494 (1994-04-01), Brode, II et al.
patent: 5304377 (1994-04-01), Yamada et al.
patent: 5306501 (1994-04-01), Viegas et al.
patent: 5330446 (1994-07-01), Weldon et al.
patent: 5350573 (1994-09-01), Goldberg et al.
patent: 5352715 (1994-10-01), Wallace et al.
patent: 5356614 (1994-10-01), Sharma
patent: 5384333 (1995-01-01), Davis et al.
patent: 5399361 (1995-03-01), Song et al.
patent: 5418222 (1995-05-01), Song et al.
patent: 5428024 (1995-06-01), Chu et al.
patent: 5437672 (1995-08-01), Allyne
patent: 5447966 (1995-09-01), Hermes et al.
patent: 5478352 (1995-12-01), Fowler
patent: 5507744 (1996-04-01), Tay et al.
patent: 5512301 (1996-04-01), Song et al.
patent: 5514379 (1996-05-01), Weissleder et al.
patent: 5516532 (1996-05-01), Atala et al.
patent: 5531759 (1996-07-01), Kensey et al.
patent: 5540715 (1996-07-01), Katsaros et al.
patent: 5648506 (1997-07-01), Desai et al.
patent: 5672336 (1997-09-01), Sharma
patent: 5674275 (1997-10-01), Tang et al.
patent: 5698213 (1997-12-01), Jamiolkowski et al.
Boyers et al., "Reduction of postoperative pelvic adhesions in the rabbit with Gore-Tex surgical membrane" Fert. Ster. (1988) 49(6):1066-1070.
Heller et al., "Release of Norethindrone from Poly(Ortho Esters)" Polymer Engineering Sci. (1981) 21:727-731.
Jeong et al., "Biodegradable block copolymers as injectable drug-delivery systems" Nature (1997) 388:860-862.
Langer et al., "Chemical and physical structure of polymers as carriers for controlled release of bioactive agents: A review" Rev. Marco Chem. Phys. (1983) C23(1):61-126.
Leong et al., "Polymeric controlled drug delivery" Adv. Drug Delivery Rev. (1987) 1:199-233.
Leong et al., "Polyanhydrides for controlled release of bioactive agents" Biomaterials (1986) 7:364-371.
Masar et al., "Synthesis of polyurethanes and investigation of their hydrolytic stability" J. Polymer Sci. (1979) 66:259-268.
Sidman et al., "Biodegradable, implantable sustained release systems based on glutamic acid copolymers" J. Membrane Science (1979) 7:227-291.

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