Radiant energy – Ionic separation or analysis – Methods
Reexamination Certificate
2006-05-23
2006-05-23
Wells, Nikita (Department: 2883)
Radiant energy
Ionic separation or analysis
Methods
C250S292000
Reexamination Certificate
active
07049580
ABSTRACT:
In the field of mass spectrometry, a method and apparatus for fragmenting ions with a relatively high degree of resolution and efficiency. The technique includes trapping the ions in a linear ion trap, in which the background or neutral gas pressure is preferably on the order of 10−5Torr. The trapped ions are resonantly excited for a relatively extended period of time, e.g., exceeding 50 ms, at relatively low excitation levels, e.g., less than 1 Volt(0-pk). The technique allows selective dissociation of ions with a high discrimination. High fragmentation efficiency may be achieved by superimposing a higher order multipole field onto the quadrupolar RF field used to trap the ions. The multipole field, preferably an octopole field, dampens the radial oscillatory motion of resonantly excited ions at the periphery of the trap. This reduces the probability that ions will eject radially from the trap thus increasing the probability of collision induced dissociation.
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Collings Bruce A.
Londry Frank
Stott William R.
Applera Corporation
Barnes & Thornburg LLC
Hughes James P.
Martin Alice C.
MDS Inc.
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