Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge
Patent
1980-10-16
1982-03-30
Prescott, Arthur C.
Chemistry: electrical and wave energy
Processes and products
Electrostatic field or electrical discharge
204301, 260112R, 260112B, 260122, 424 12, 424 36, 424101, 424177, 23902, 128214B, 128DIG22, 210927, B01D 1302, A23J 106, A61K 3704
Patent
active
043222757
ABSTRACT:
This invention relates to the separation of complex protein mixtures by lowering (desalting) or by raising (salting-out) their electrolytic (ionic) concentration by electrodialysis followed by chilling, pH adjustment, filtration, and/or centrifugation and optionally thereafter restoration of the lost electrolyte or removal of the gained electrolyte and water. This technique is especially adaptable for therapeutic plasma exchange performed in situ for immunepheresis i.e. removal of globulin or immunecomplexes implicated in autoimmune diseases. The techniques are also applicable for antihemophilic factor separation and purification, and separation of proteins from whey.
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Ionics Incorporated
Prescott Arthur C.
Saliba Norman E.
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