Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Reexamination Certificate
2002-05-31
2010-10-12
Desai, Anand U (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
C530S300000, C514S002600
Reexamination Certificate
active
07812138
ABSTRACT:
Thus, a primary aspect of the present invention relates to a method for the fractionation of a protein-containing mixture wherein the protein-containing mixture is selected from the group consisting of milk, milk derived products, milk derived raw materials, vegetable derived products, vegetable derived extracts, fruit derived products, fruit derived extracts, fish derived products, and fish derived extracts, the method comprising the steps of: a) optionally adjusting the pH of the mixture; b) applying the mixture to an adsorption column comprising an adsorbent, the adsorbent comprises a particle with at least one high density non-porous core, surrounded by a porous material, the adsorbent having a particle density of at least 1.5 g/ml and a mean particle size of at most 150 μm; c) optionally washing the column; d) eluting at least one protein from the adsorbent.
REFERENCES:
patent: 4452773 (1984-06-01), Molday
patent: 4791193 (1988-12-01), Okonogi et al.
patent: 4976865 (1990-12-01), Sanchez et al.
patent: 5516675 (1996-05-01), Uchida et al.
patent: 5522993 (1996-06-01), Carlsson et al.
patent: 5596082 (1997-01-01), Kussendrager et al.
patent: 5986063 (1999-11-01), Etzel
patent: 6620326 (2003-09-01), Lihme et al.
patent: 6783962 (2004-08-01), Olander et al.
patent: 7368141 (2008-05-01), Lihme
patent: 2004/0140265 (2004-07-01), Lihme
patent: 2005/0220953 (2005-10-01), Lihme
patent: 0 538 350 (1993-04-01), None
patent: 1 586 364 (1981-03-01), None
patent: WO 86/03136 (1986-06-01), None
patent: WO 92/00799 (1992-01-01), None
patent: WO 92/16292 (1992-10-01), None
patent: WO 92/18237 (1992-10-01), None
patent: WO 93/13676 (1993-07-01), None
patent: WO 97/17132 (1997-05-01), None
patent: WO 98/08603 (1998-03-01), None
patent: WO 98/33572 (1998-08-01), None
patent: WO 99/15024 (1999-04-01), None
patent: WO 99/65586 (1999-12-01), None
patent: WO 00/57982 (2000-10-01), None
patent: WO 01/85329 (2001-11-01), None
Rossomando, E. Methods in Enzymology 182: 309-317 (1990).
Griffith et al. Journal of Chromatography A 776: 179-195 (1997). “Fluidization characteristics of and protein adsorption on fluoride-modified porous zirconium oxide particles”.
Straetkvern et al., “Expanded bed adsorption for recovery of patatin from crude potato juice”, Bioseparation 7: 333-345 (1999).
Anspach et al., “Expanded-bed chromatography in primary protein purification”, Journal of Chromatrography A 865: 129-144 (1999).
Burns et al., Biotechnol. Bioengin. 27 (1985) 137-145.
J. Porath et al. FEBS Letters, vol. 185, p. 306, Jun. 1985.
K.L. Knudsen et al. Analytical Biochemistry, vol. 201, p. 170, Oct. 1991.
J. Porath et al., Makromol. Chem., Makromal. Symp., vol. 17, p. 359, 1988.
A. Schwarz et al. Journal of Chromatography B, vol. 664, pp. 83-88, 1995.
Andersen Inga Vaarst
Hansen Marie Bendix
Lihme Allan Otto Fog
Olander Morten Aae
Desai Anand U
Merchant & Gould P.C.
Upfront Chromatography A/S
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