Fractionation of protein containing mixtures

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S300000, C514S002600

Reexamination Certificate

active

07812138

ABSTRACT:
Thus, a primary aspect of the present invention relates to a method for the fractionation of a protein-containing mixture wherein the protein-containing mixture is selected from the group consisting of milk, milk derived products, milk derived raw materials, vegetable derived products, vegetable derived extracts, fruit derived products, fruit derived extracts, fish derived products, and fish derived extracts, the method comprising the steps of: a) optionally adjusting the pH of the mixture; b) applying the mixture to an adsorption column comprising an adsorbent, the adsorbent comprises a particle with at least one high density non-porous core, surrounded by a porous material, the adsorbent having a particle density of at least 1.5 g/ml and a mean particle size of at most 150 μm; c) optionally washing the column; d) eluting at least one protein from the adsorbent.

REFERENCES:
patent: 4452773 (1984-06-01), Molday
patent: 4791193 (1988-12-01), Okonogi et al.
patent: 4976865 (1990-12-01), Sanchez et al.
patent: 5516675 (1996-05-01), Uchida et al.
patent: 5522993 (1996-06-01), Carlsson et al.
patent: 5596082 (1997-01-01), Kussendrager et al.
patent: 5986063 (1999-11-01), Etzel
patent: 6620326 (2003-09-01), Lihme et al.
patent: 6783962 (2004-08-01), Olander et al.
patent: 7368141 (2008-05-01), Lihme
patent: 2004/0140265 (2004-07-01), Lihme
patent: 2005/0220953 (2005-10-01), Lihme
patent: 0 538 350 (1993-04-01), None
patent: 1 586 364 (1981-03-01), None
patent: WO 86/03136 (1986-06-01), None
patent: WO 92/00799 (1992-01-01), None
patent: WO 92/16292 (1992-10-01), None
patent: WO 92/18237 (1992-10-01), None
patent: WO 93/13676 (1993-07-01), None
patent: WO 97/17132 (1997-05-01), None
patent: WO 98/08603 (1998-03-01), None
patent: WO 98/33572 (1998-08-01), None
patent: WO 99/15024 (1999-04-01), None
patent: WO 99/65586 (1999-12-01), None
patent: WO 00/57982 (2000-10-01), None
patent: WO 01/85329 (2001-11-01), None
Rossomando, E. Methods in Enzymology 182: 309-317 (1990).
Griffith et al. Journal of Chromatography A 776: 179-195 (1997). “Fluidization characteristics of and protein adsorption on fluoride-modified porous zirconium oxide particles”.
Straetkvern et al., “Expanded bed adsorption for recovery of patatin from crude potato juice”, Bioseparation 7: 333-345 (1999).
Anspach et al., “Expanded-bed chromatography in primary protein purification”, Journal of Chromatrography A 865: 129-144 (1999).
Burns et al., Biotechnol. Bioengin. 27 (1985) 137-145.
J. Porath et al. FEBS Letters, vol. 185, p. 306, Jun. 1985.
K.L. Knudsen et al. Analytical Biochemistry, vol. 201, p. 170, Oct. 1991.
J. Porath et al., Makromol. Chem., Makromal. Symp., vol. 17, p. 359, 1988.
A. Schwarz et al. Journal of Chromatography B, vol. 664, pp. 83-88, 1995.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Fractionation of protein containing mixtures does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fractionation of protein containing mixtures, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fractionation of protein containing mixtures will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4160878

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.