Fractionating apparatus having colonies of pillars arranged...

Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus

Reexamination Certificate

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Details

C204S164000, C204S549000, C204S450000, C430S311000, C435S287300, C435S283100

Reexamination Certificate

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06881315

ABSTRACT:
A fractionating apparatus is used for fractionating sample into micro-structures different in size, and includes a fractionating unit formed with a fractionating passage; the fractionating passage is defined in a groove formed in a substrate of the fractionating unit, and pillar patches are formed in the groove at intervals wider than the gap among the pillar patches; while the sample is migrated through the fractionating passage, small-sized DNA molecules are trapped in the pillar patches, and large-sized DNA molecules are smoothly migrated through the wide intervals; this results in that the large-sized DNA molecules reaches the end of the fractionating passage faster than the small-sized DNA molecules without clogging.

REFERENCES:
patent: 5427663 (1995-06-01), Austin et al.
patent: 5837115 (1998-11-01), Austin et al.
patent: 10-506991 (1998-07-01), None
patent: 2002-233792 (2002-08-01), None
patent: 2002-239317 (2002-08-01), None
patent: WO9909042 (1999-02-01), None
Japanese Office Action dated Jun. 1, 2004.

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