Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus
Reexamination Certificate
2005-04-19
2005-04-19
McPherson, John A. (Department: 1756)
Chemistry: electrical and wave energy
Apparatus
Electrophoretic or electro-osmotic apparatus
C204S164000, C204S549000, C204S450000, C430S311000, C435S287300, C435S283100
Reexamination Certificate
active
06881315
ABSTRACT:
A fractionating apparatus is used for fractionating sample into micro-structures different in size, and includes a fractionating unit formed with a fractionating passage; the fractionating passage is defined in a groove formed in a substrate of the fractionating unit, and pillar patches are formed in the groove at intervals wider than the gap among the pillar patches; while the sample is migrated through the fractionating passage, small-sized DNA molecules are trapped in the pillar patches, and large-sized DNA molecules are smoothly migrated through the wide intervals; this results in that the large-sized DNA molecules reaches the end of the fractionating passage faster than the small-sized DNA molecules without clogging.
REFERENCES:
patent: 5427663 (1995-06-01), Austin et al.
patent: 5837115 (1998-11-01), Austin et al.
patent: 10-506991 (1998-07-01), None
patent: 2002-233792 (2002-08-01), None
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patent: WO9909042 (1999-02-01), None
Japanese Office Action dated Jun. 1, 2004.
Baba Masakazu
Iguchi Noriyuki
Iida Kazuhiro
Kawaura Hisao
Sakamoto Toshitsugu
Chacko-Davis Daborah
McPherson John A.
NEC Corporation
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