Fractionated polyalkylene oxide-conjugated hemoglobin solutions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530385, A61K 3842, C07K 1405

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active

056503881

ABSTRACT:
Polyalkylene oxide-conjugated hemoglobin solutions having a molecular weight greater than about 85,000 daltons and a degree of substitution of which substantially avoids clinically significant nephrotoxicity associated with hemoglobinuria in mammals. A method of simultaneously fractionating and purifying polyalkylene oxide-conjugated hemoglobins is al so disclosed.

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