Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Chemical analysis
Patent
1991-11-15
1999-12-14
Kemper, Melanie A.
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Chemical analysis
702 23, B01D 1508, G01N 2100
Patent
active
060029862
ABSTRACT:
A detection signal from a multi-wavelength detector provided in a liquid chromatograph is stored in a data storage part, and a chromatogram is formed from the stored data with respect to a specific wavelength, to detect a peak from the chromatogram. The spectrum at a top of the peak to be identified or a known spectrum of a component to be identified is used as a reference spectrum, to calculate the degree of coincidence between the spectrum at each position of the chromatogram peak and the reference spectrum as fraction purity at each position of the chromatogram peak. The calculated fraction purity values are classified in colors, for example, and displayed on a display part. Thus, it is possible to readily decide whether the measured peak consists of a single component or at least two components, and which time range consists of a single component.
REFERENCES:
patent: 3504174 (1970-03-01), Nisiwaki et al.
patent: 4367041 (1983-01-01), Webb, Jr. et al.
patent: 4482966 (1984-11-01), Mito et al.
patent: 4760331 (1988-07-01), Komuro et al.
patent: 4766551 (1988-08-01), Begley
patent: 4835708 (1989-05-01), Frans
patent: 5175430 (1992-12-01), Enke et al.
Publication--Quantitative Resolution of Fused Chromatographic Peaks in Gas Chromatography/Mass Spectrometry, Muhammad Abdallah Sharaf et al., Anal. Chem. 1982.
Publication--Use of Multivariate Curve Resolution and a High-Speed Diode Array Ultraviolet Detector in Size-Exclusion Chromatography of Lignin-Based Copolymers, John C. Nicholson et al., Anal. Chem. 1984.
Zech, Karl and Reinhard Huber, "On-Line Screening for Drug Metabolites by High Performance Liquid Chromatography with a Diode Array UV Detector", Journal of Chromatography, 282 pp. 161-167, 1983.
Marr, J.G.D et al., "Multiple Absorbance Ratio Correlation--A New Approach for Assessing Peak Purity in Liquid Chromatography" Journal of Chromatography, 506 pp. 289-301, May 1990.
Yost, Roy, Stoveken, John and William MacLean, "Positive Peak Identification in Liquid Chromatography Using Absorbance Ratioing with a Variable-Wavelength Spectrophotometric Detector", Journal of Chromatography, 134, pp. 73-82, 1177.
Kemper Melanie A.
Shimadzu Corporation
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