Image analysis – Applications – Biomedical applications
Reexamination Certificate
2008-05-13
2008-05-13
Werner, Brian (Department: 2624)
Image analysis
Applications
Biomedical applications
C382S154000, C382S294000
Reexamination Certificate
active
07372984
ABSTRACT:
When the studied motion is periodic, such as for a beating heart, it is possible to acquire successive sets of two dimensional plus time data slice-sequences at increasing depths over at least one time period which are later rearranged to recover a three dimensional time sequence. Since gating signals are either unavailable or cumbersome to acquire in microscopic organisms, the invention is a method for reconstructing volumes based solely on the information contained in the image sequences. The central part of the algorithm is a least-squares minimization of an objective criterion that depends on the similarity between the data from neighboring depths. Owing to a wavelet-based multiresolution approach, the method is robust to common confocal microscopy artifacts. The method is validated on both simulated data and in-vivo measurements.
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Dickinson Mary
Farouhar Arian
Fraser Scott E.
Gharib Morteza
Liebling Michael
California Institute of Technology
Dawes Daniel L.
Mackowey Anthony
Myers Dawes Andras and Sherman LLP
Werner Brian
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