Fortimicins AM and AP

Details Fortimicins AM and AP Fortimicins AM and AP

1979-03-29

1980-07-22

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 18, A61K 3171, C07H 1522

Patent

active

042140803

ABSTRACT:
Novel fortimicins, fortimicin AM and fortimicin AP are represented by the formula ##STR1## wherein R.sub.1 is hydrogen or hydroxy and R.sub.2 is hydrogen when R.sub.1 is hydroxy and hydroxy when R.sub.1 is hydrogen. Fortimicins AM and AP are coproduced with fortimicin A, fortimicin B and other minor factors in the fermentation of Micromonospora olivoasterospora. The compounds are useful as intermediates for 4-N-substituted fortimicins AP and AM which are useful as antibacterial agents.

REFERENCES:
patent: 4091032 (1978-05-01), Tadanier et al.
patent: 4124756 (1978-11-01), Martin et al.

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