Fortimicin AN

Details Fortimicin AN Fortimicin AN

1979-03-29

1980-08-26

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 424181, 536 18, 435 80, A61K 3171, C07H 1522

Patent

active

042196434

ABSTRACT:
Fortimicin AN is coproduced with fortimicin A, fortimicin B and a number of other minor factors in the fermentation of Micromonospora olivoasterospora ATCC Nos. 21819, 31009 or 31010. Structurally, fortimicin AN is 1-N-glycyl-3-O-demethylfortimicin B. The compound is useful as an intermediate for 3-O-demethylfortimicin B which is readily obtained by hydrolysis of fortimicin AN in base.

REFERENCES:
patent: 3878193 (1975-04-01), Reimann
patent: 3963695 (1976-06-01), Cooper et al.
patent: 4091032 (1978-05-01), Tadanier et al.
patent: 4124756 (1978-11-01), Martin et al.

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