Fortimicin aminoglycosides, process for production thereof, and

Details Fortimicin aminoglycosides, process for production thereof, and Fortimicin aminoglycosides, process for production thereof, and

1979-10-12

1981-03-10

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 4, 536 17R, A61K 3171, C07H 1522

Patent

active

042554217

ABSTRACT:
Novel aminoglycosides of the following formula ##STR1## wherein R.sub.1 and R.sub.2 are identical or different and each represents a hydrogen atom or a methyl group, R.sub.3 represents a hydrogen atom or an optionally substituted aminoacyl group having 2 to 4 carbon atoms in the acyl moiety, and when all of R.sub.1, R.sub.2 and R.sub.3 are hydrogen atoms, the methylamino group at the 4-position is not oriented trans to the hydroxyl groups at the 3- and 5-positions; and acid addition salts thereof, which are useful as antibiotics; and process for producing compounds containing the same.

REFERENCES:
patent: 4124756 (1978-11-01), Martin et al.
patent: 4169942 (1979-10-01), Mochida et al.

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