Formyl derivatives of hydrazinopenicillins

Details Formyl derivatives of hydrazinopenicillins Formyl derivatives of hydrazinopenicillins

1980-12-29

1982-05-11

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, C07D49968, C07D49970

Patent

active

043292852

ABSTRACT:
Formyl derivatives of hydrazinopenicillins of the formula ##STR1## wherein R is thienyl or phenyl, R' is hydrogen, formyl or alkyl containing from 1 to 3 carbon atoms and R" is hydrogen or formyl, provided that at least one of R' and R" is a formyl group, the carbon atom with the asterisk indicating a center of asymmetry of the molecule, and pharmaceutically acceptable salts and esters thereof, as mixture or as separated epimers. These compounds have antibacterial activity against Gram-negative and Gram-positive bacteria and are prepared by a process wherein the corresponding hydrazinopenicillin is reacted under anhydrous conditions with acetoformic anhydride to give the desired compounds.

REFERENCES:
patent: 3174964 (1965-03-01), Hobbs et al.
patent: 4008220 (1977-02-01), Tobiki et al.
patent: 4231927 (1980-11-01), Monguzzi et al.

Affiliated with

Also associated with

Rating

Formyl derivatives of hydrazinopenicillins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Formyl derivatives of hydrazinopenicillins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Formyl derivatives of hydrazinopenicillins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-755462