Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1988-09-30
1990-02-27
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424458, 424461, 424462, A61K 964
Patent
active
049044761
ABSTRACT:
A therapeutic preparation consisting of three groups of spheroids containing an active medicinal substance. The first group of spheroids is uncoated and rapidly disintegrates upon ingestion to release an initial dose of medicinal substance a second group of spheroids is coated with a pH sensitive coat to provide a second dose and a third group of spheroids is coated with a pH independent coat to provide a third dose. A powder blend of active medicinal substance may be substituted for the first group of uncoated spheroids. The therapeutic preparation may be utilized as a mixture of groups of spheroids in a capsule.
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Bachand Lizbeth A.
Leonard Thomas W.
Mehta Atul M.
Warner Ronald N.
American Home Products Corporation
Page Thurman K.
Routh John W.
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