Formulations for use in medical and diagnostic procedures

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing

Reexamination Certificate

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Details

C424S001110, C424S001730, C424S001650, C424S009300, C424S009400

Reexamination Certificate

active

10476314

ABSTRACT:
The present invention relates to formulations for use in medical or diagnostic procedures comprising a stabilizing agent alone or in combination with an osmotic agent. In one embodiment, the stabilizing agent is a natural hydrocolloid, preferably locust bean gum, and the osmotic agent is a sugar-based compound, preferably mannitol. The present invention also relates to formulations and methods for distending an anatomic segment. The present invention further relates to formulations and methods for delineating an anatomic segment on a diagnostic image, for example. The formulations of the present invention are especially suitable for use with diagnostic imaging procedures including, but not limited to magnetic resonance imaging (MR), computer assisted tomography (CT), and CT-PET (Position emission tomography), as well as other medical and therapeutic uses.

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Ogawa, Process in Colloid & Polymer Science, 1999, vol. 114 (Physical Chemistry and Industrial Application of Gellan Gum), pp. 8-14.
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Search Report from corresponding International Application No. PCT/US02/37385 dated May 23, 2003.

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