Formulations for sustained release dressings and their use

Details Formulations for sustained release dressings and their use Formulations for sustained release dressings and their use

1992-05-26

1996-01-02

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424443, 424445, 424425, 514947, A61K 910, A61K 970, A61K 4734, A61L 1526

Patent

active

054806534

ABSTRACT:
The invention concerns a sustained release formulation comprising an agent (A) which is to be released and a vehicle (B) therefor.
The vehicle comprises a hydrophilic component such as a polyhydroxylated organic substance such as a polyethylene glycol, glycerol, sorbitol, mannitol or lactose and curable silicone composition which is capable of curing at ambient temperature and contains a polysiloxane having alkylhydrogen units, a polysiloxane having unsaturated groups and a platinum or rhodium catalyst. The formulation may be applied to the human or animal body or a cavity in the latter to cure in situ to give a dressing capable of sustained release of the therapeutic or diagnostic agent (A) to the body.
The invention is applicable in the field of pharmacy.

REFERENCES:
patent: 3996934 (1976-12-01), Zaffaroni
patent: 4053580 (1977-10-01), Chien et al.
patent: 4189546 (1980-02-01), Deichert et al.
patent: 4230686 (1980-10-01), Schopflon et al.
patent: 4814184 (1989-03-01), Aguadisch et al.

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