Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1992-12-17
1994-07-05
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
424 5, 424489, 424499, 514 5, 514718, 514975, A61K 4904, A61K 914, A61K 950
Patent
active
053265521
ABSTRACT:
The present invention is directed to a composition comprised of nanoparticles containing an X-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith.
The present invention is still further directed to a method for diagnostic imaging for use in medical procedures comprising administering to the body of a test subject in need of an X-ray an effective contrast producing amount of a composition comprised of nanoparticles containing an X-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith.
REFERENCES:
patent: 3997470 (1976-12-01), Monte et al.
patent: 4406878 (1983-09-01), De Boer
patent: 4540602 (1985-09-01), Motoyama et al.
patent: 5114703 (1992-05-01), Wolf et al.
patent: 5145684 (1992-09-01), Liversidge et al.
Na George C.
Rajagopalan Natarajan
Davis William J.
Hollinden Gary E.
Sterling Winthrop Inc.
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